Methylene blue leak test for Blisters and Pouches – CTE-BI
Pharmaceutical Leak Detector
Its allows to test, by depression, and thanks in particular to the migration of a tracer product called blue methylene, the sealing of blister-type samples or sleeves.
It is generally used in the pharmaceutical factory, sector in which the blister packaging is flagship.
Description
Visual Leak Testing Using Methylene Blue Dye
The CTE-BI is a manual vacuum chamber designed specifically for the methylene blue leak test, a destructive visual method used to evaluate the integrity of sealed packaging such as blister packs, pouches, and sachets.
This technique is widely accepted in pharmaceutical, food, and cosmetic industries to ensure product safety and packaging integrity.
✅ What is the Methylene Blue Leak Tester?
The methylene blue leak testing involves immersing a package in a blue dye solution and applying vacuum pressure. If a seal or material defect is present, the dye will visibly enter the packaging.
This method is:
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Qualitative and destructive
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Simple to implement
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Effective for detecting micro-leaks
🔗 Learn more about our standard CTE vacuum testers.
🔧 Technical Features
| Feature | Specification |
|---|---|
| Test method | Methylene blue leak test |
| Vacuum range | 0 to -875 mbar |
| Chamber material | Transparent PMMA |
| Chamber sizes available | Custom (e.g., 300×250×200 mm) |
| Vacuum control | Manual, with analog manometer |
| Dye container | Removable tray, easy to clean |
| Optional features | Timer (up to 10 minutes), vacuum pump |
🧪 Applications of Methylene Blue Leak Test
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Blister packs for tablets and capsules
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Doypacks and flexible food packaging
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Cosmetic sachets and medical pouches
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Small sealed containers requiring GMP leak validation
💡 Why Use the CTE-BI?
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Reproducible methylene blue leak testing under controlled vacuum
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Fully manual and cost-efficient
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Transparent chamber for easy observation
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Compatible with internal or external vacuum sources
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Quick integration in quality control workflows
🔗 External reference: Discover the standard test method ASTM F3039
